Acyl Halides
Medchemexpress LLC TL8-506 | 1268163-15-0 | 95.0% | 331.37 | 5 MG
TL8-506 is a specific TLR8 agonist with an EC50 of 30 nM. It has immunomodulatory effects and can be used in the study of tuberculosis and cancer immunotherapy. It can activate dendritic cells, induce pro-inflammatory cytokines, and enhance resistance to *Mycobacterium tuberculosis* infection.
- Specific TLR8 agonist
- Immunomodulatory effects
- Used in tuberculosis research
- Used in cancer immunotherapy research
- Activates dendritic cells in blood and tumors
- Induces secretion of pro-inflammatory cytokines and chemokines
- Promotes activation and recruitment of T cells
- Enhances resistance to *Mycobacterium tuberculosis* infection
- Lowers bacterial load in lungs and livers
- Ameliorates tuberculous pneumonia and alveolitis
- Reduces numbers and area of granulomas
- Increases proportion of central memory CD8+ T cells
Medchemexpress LLC IEM 1925 dihydrobromide | 258282-23-4 | 98.0% | 422.24 | C17H30Br2N2 | 5 MG
IEM-1925 dihydrobromide is the dihydrobromide salt of IEM-1925, a use- and voltage-dependent open-channel antagonist of AMPA (glutamate) receptors. It is supplied as a high-purity solid for research use in pharmacology, electrophysiology, and seizure-model studies.
- Chemical formula: C17H30Br2N2.
- Cas number: 258282-23-4.
- Molecular weight: 422.24.
- Purity: 98.0%.
- Appearance: solid.
- Typical applications: AMPA receptor pharmacology and seizure-model research.
- Available pack sizes: 5 mg, 10 mg.
Medchemexpress LLC Tiotropium bromide | 136310-93-5 | 472.42 | 1 ML
Tiotropium bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. It is a 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. It improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
- Targets mAChR
- Involved in GPCR/G Protein and neuronal signaling pathways
- Long-acting, stops signaling between neurons and leads to muscle relaxation
- Used in the management of chronic obstructive pulmonary disease
- Improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure
AdipoGen Stain 7-II
Chemical. CAS 155863-03-9. Formula C29H24BrN3O6. MW 590.42. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance.
Medchemexpress LLC Oleyl bromide ((Z)-1-Bromooctadec-9-ene) | 6110-53-8 | 98.4% | 331.37 | 25 MG
Oleyl bromide is a hydrophobic compound that can carry out ring-opening reaction through a process called 'encapsulation.' It can also be used as the starting material in the synthesis of oleylphosphonates.
- Hydrophobic compound
- Can carry out ring-opening reactions
- Used as starting material in synthesis of oleylphosphonates
- For research use only
- Biochemical assay reagent
Cayman Chemical QX314 bromide Other Receptor
A membrane-impermeant lidocaine derivative that when combined with capsaicin selectively blocks sodium channels on nociceptive neurons via the TRPV1 channel; decreases the pain response without imparting numbness or paralysis associated with other local anesthetics
Medchemexpress LLC Rapacuronium bromide | 156137-99-4 | 98.0% | 677.80 | 1 ML
Rapacuronium bromide (Org 9487) is a non-depolarizing neuromuscular blocker that also acts as an allosteric modulator of the muscarinic acetylcholine receptor (mAChR). It is intended for research use only.
- Acts as a non-depolarizing neuromuscular blocker.
- Functions as an allosteric modulator of the muscarinic acetylcholine receptor (mAChR).
- Binds to all muscarinic receptor subtypes.
- Shows micromolar affinity and slight selectivity towards the M2 receptor.
- Exhibits neuromuscular effects in vivo.
Medchemexpress LLC Fentonium bromide | 5868-06-4 | 98.8% | 100MG
Fentonium bromide | 5868-06-4 | 98.8% | 100MG
AdipoGen 4-ITCB-MPO-pyridinium bromide
Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
Cayman Chemical N4-benzoyl-2-DeoxycytIdIn 25g
A building block; has been used in the synthesis of nucleosides and nucleotides with anticancer activity, as well as oligonucleotides
Medchemexpress LLC Domiphen bromide | 538-71-6 | 98.7% | 1 ML
Domiphen bromide is a cationic active quaternary ammonium salt that inhibits HERG channels, aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. It exhibits antibacterial, antimalarial, and disinfectant properties, and acts as a synergist for Colistin. This compound can be utilized as a chemical preservative and cationic surfactant, and is also relevant for research into bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers.
- Cationic active quaternary ammonium salt
- Inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin
- Antibacterial, antimalarial, and disinfectant properties
- Synergist of colistin
- Can be used as a chemical preservative and cationic surfactant
- Applicable in research of bacterial infectious diseases like pharyngitis, thrush, and oral ulcers
AdipoGen Stain 7-II
Chemical. CAS 155863-03-9. Formula C29H24BrN3O6. MW 590.42. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance.
Medchemexpress LLC N4-Benzoyl-2 -O-meth 5g
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
Medchemexpress LLC Demecarium bromide | 56-94-0 | 95.0% | 1 ML
Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor known for its apparent affinity (Kiapp) of 0.15 μM. It serves as a glaucoma agent, effective in both normotensive and inherited glaucoma conditions. In vivo studies demonstrate its ability to cause long-term miosis and decrease intraocular pressure.
- Potent cholinesterase inhibitor
- Apparent affinity (Kiapp) of 0.15 μM
- Used as a glaucoma agent
- Causes long-term miosis
- Decreases intraocular pressure (IOP)